Course Title:
Solid Mechanics of Cells and Tissues
Course Description:
Focuses on the multiscale mechanical behavior of biological tissues. The mechanical integrity of a single cell depends on the mechanical properties and geometrical arrangements of the fiber network in the extracellular matrix. Introduces the statistical concept of persistent length and entanglement of long-chain polymer molecules, linear elasticity and viscoelasticity, membrane undulations, stability of vesicles. Discusses the intersurface forces that cause cells to adhere and to form microscopic, mesoscopic, and macroscopic two-dimensional membranes and three-dimensional structures. Introduces experimental techniques and measurements involving atomic force microscope, surface force apparatus, optical tweezers, micropipette aspiration. Provides examples for specific physiological and path-physiological phenomena related to mechanical and adhesion behavior of cells and membranes.
Fall Offering:
Every
Lab/Coreq 1:
Spring Offering:
Lab/Coreq 2:
Summer Offering:
Lab/Coreq Remarks:
Summer 1 Offering:
Prerequisite 1:
MIM U355
Summer 2 Offering:
Prerequisite 2:
Cross-Listed Course 1:
MTM G223
Prerequisite 3:
Cross-Listed Course 2:
Prerequisite 4:
Cross-Listed Course 3:
Prerequisite 5:
Cross-Listed Course 4:
Prerequisite Remarks:
Cross-Listed Course 5:
Repeatable:
N
